Peripheral Ossifying Fibroma Advanced Out-of Pyogenic Granuloma

Peripheral Ossifying Fibroma Advanced Out-of Pyogenic Granuloma

Mention this particular article as: Godinho Grams V, Silva C An effective, Noronha B Roentgen, et al. () Peripheral Ossifying Fibroma Evolved Of Pyogenic Granuloma. Cureus fourteen(1): e20904. doi:/cureus.20904


The purpose of today’s blog post is to try to introduce new systematic matter of an enormous peripheral ossifying fibroma one changed off an excellent before detected pyogenic granuloma in the a good 50-year-dated woman. Individual is actually called to have treatments for an effective lesion over the buccal and you may palatal gingiva around the kept top very first molar. It was purplish-red into the color, up to step three cm for the diameter, with a delicate epidermis, a good pedicled and you can hemorrhaging ft, which have eight several years of advancement, and you will identified because pyogenic granuloma. Once three-years regarding evasion, the person came back revealing an increase in the brand new lesion and you can problem into the dining. Medically the latest nodule is actually lobular to look at, pink from inside the color and you can simple, pediculated, corporation within the consistency, non-bleeding, regarding 5 cm in its finest expansion, extending on the maxillary tuberosity. The latest lesion is actually excised and known for histopathological examination, which triggered the analysis of peripheral ossifying fibroma. The individual are implemented for around eighteen months, prosthetically rehabilitated, with high enough recovery no health-related signs and symptoms of recurrence.

The brand new you’ll progression of a beneficial pyogenic granuloma to an excellent peripheral ossifying fibroma are present in this case, according to research by the histopathological change that happened, to the development of calcified question, stringy maturation, and diminished vascular blogs of initial lesion immediately following 3 years.


Pyogenic granuloma (PG) ’s the second typical reactive lesion of one’s jaws, after inflammatory stringy hyperplasia, the most widespread activated lesion. PG gift ideas a highly-circumscribed and you can distinct lobular plan, that have large main ships and you can better-formed peripheral capillary aggregates. When unattended, which lesion can also be proceed through fibrous maturation having ossification and create with the peripheral ossifying fibroma .

Peripheral ossifying fibroma (POF) are a harmless mesenchymal lesion, commonplace regarding the prior maxillary gingiva of women involving the second and you may 3rd years away from life. It is experienced an excellent metaplastic process that requires the periodontal ligament responding in order to trauma otherwise local irritants, such as for example biofilm, calculus, badly adjusted prostheses, and you can unsatisfactory restorations [dos,3]. The fresh new advancement off PG so you can POF try told me with regards to medical and you will histopathological parallels; yet not, you will need to remember that not absolutely all POF evolves regarding a good PG. The newest mineralized component designed may vary among cementum, bone, and dystrophic calcification .

So it declaration presents the way it is out-of a huge peripheral ossifying fibroma one changed regarding an effective lesion in the past detected because the pyogenic granuloma when you look at the a great 50-year-dated woman.

Circumstances Demonstration

A beneficial 50-year-dated hypertensive woman is referred to the brand new Dental and you may Maxillofacial Businesses and you may Traumatology outpatient clinic of Mato Grosso Cancer Medical, Cuiaba, Brazil, to own treatments for an effective maxillary lesion, identified because the PG, due to the fact demonstrated by histopathological examination of an enthusiastic incisional biopsy did in past times. The brand new microscopic dysfunction contained good fragment regarding mucosa covered by stratified hyperparakeratinized squamous epithelium, having aspects of acanthosis and you can much time projections, spongiosis, exocytosis, and ulceration. The new lamina propria is formed of the thick conjunctive structure, that have aspects of intense cellularity and you may growth regarding endothelial tissues are detailed, that have opening regarding vascular rooms and you may aspects of severe chronic inflammatory infiltrate that have hemorrhagic components (Contour step 1).

Profile step one: Histological picture of pyogenic granuloma demonstrating hyperparakeratinized stratified squamous epithelium, with areas of acanthosis and you will much time forecasts.

Lamina propria molded by thick conjunctive cells, detailing aspects of severe cellularity and proliferation away from endothelial tissues, having opening from vascular rooms and you will areas of intense chronic inflammatory penetrate that have hemorrhagic parts (Haemotoxylin and you can Eosin, 100x).

Clinically, she exhibited a great nodule across the buccal and palatal gingiva intimate left top first molar, around 3 cm in the diameter, having a mellow body, purplish-red color, pedicled and you can hemorrhaging feet which have 7 numerous years of progression. From the recommendation, discover and the diagnosis regarding significant chronic periodontitis, observing, into the intraoral physical examination, terrible oral health and you may general enamel flexibility.

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